Life ‘Who’s the Boss?’ sequel: Everything we know about the cast, storyline, more August 5, 2020Entertain This!, USA TODAYComments Off on ‘Who’s the Boss?’ sequel: Everything we know about the cast, storyline, more Tony Danza and Alyssa Milano will star in a "Who's the Boss?" TV sequel. It could join a list of other successful 80's reboots.