News Xylazine, an animal tranquilizer, is a new threat in the opioid epidemic: What we know January 24, 2023Adrianna Rodriguez, USA TODAYComments Off on Xylazine, an animal tranquilizer, is a new threat in the opioid epidemic: What we know The animal tranquilizer xylazine is showing up in the illicit drug supply in the United States, particularly in synthetic opioids like fentanyl.